Elevated homocysteine (Hcy) due to common gene variants is correlated with coronary heart disease (CHD), but definite causality remains uncertain. Hcy increases due to genetic and environment interactions. Assuming no direct effects of folate on CHD except via increased Hcy, and that folate drives Hcy metabolism, investigating on how genes influence folate balancing is strongly useful. DHFR and MTHFR fully activate diet folate. Common polymorphisms influence activity/level of enzymes. MTHFR677TT reduces enzyme efficiency yielding ~20% higher Hcy. Less definitive is the role ascribed to DHFR 19bp ins/del; some authors reported ~50% higher mRNA in del/del genotype. We selected 14 CHD patients from our Center carrying opposite DHFR/MTHFR geno...
<FONT FACE="Arial"><strong>Background</strong> Homocysteine is a sulfur-containing amino acid formed...
BACKGROUND: Moderately elevated blood levels of homocysteine are weakly correlated with coronary hea...
Background Moderately elevated blood levels of homocysteine are weakly correlated with coronary hear...
Hyperhomocysteinemia appears to be an independent risk factor for coronary disease. Elevated levels ...
Objectives Alterations in the enzymes involved in homocysteine (Hcy) metabolism or vitamin deficienc...
Objectives Alterations in the enzymes involved in homocysteine (Hcy) metabolism or vitamin deficienc...
Alterations in the enzymes involved in homocysteine (Hcy) metabolism or vitamin deficiency could pla...
Moderately elevated blood levels of homocysteine are weakly correlated with coronary heart disease (...
Common chronic diseases including cardiovascular disease (CVD) are the leading cause of morbidity an...
Folate deficiency is strongly associated with cardiovascular disease. We aimed to explore the joint ...
Folate deficiency is strongly associated with cardiovascular disease. We aimed to explore the joint ...
Moderate elevation of plasma total homocysteine (tHcy) is a strong and independent risk factor for c...
Elevated plasma total homocysteine (hcy), a risk factor for Coronary Artery Disease (CAD), is due to...
BACKGROUND: Moderately elevated blood levels of homocysteine are weakly correlated with coronary hea...
Background: Moderately elevated blood levels of homocysteine are weakly correlated with coronary hea...
<FONT FACE="Arial"><strong>Background</strong> Homocysteine is a sulfur-containing amino acid formed...
BACKGROUND: Moderately elevated blood levels of homocysteine are weakly correlated with coronary hea...
Background Moderately elevated blood levels of homocysteine are weakly correlated with coronary hear...
Hyperhomocysteinemia appears to be an independent risk factor for coronary disease. Elevated levels ...
Objectives Alterations in the enzymes involved in homocysteine (Hcy) metabolism or vitamin deficienc...
Objectives Alterations in the enzymes involved in homocysteine (Hcy) metabolism or vitamin deficienc...
Alterations in the enzymes involved in homocysteine (Hcy) metabolism or vitamin deficiency could pla...
Moderately elevated blood levels of homocysteine are weakly correlated with coronary heart disease (...
Common chronic diseases including cardiovascular disease (CVD) are the leading cause of morbidity an...
Folate deficiency is strongly associated with cardiovascular disease. We aimed to explore the joint ...
Folate deficiency is strongly associated with cardiovascular disease. We aimed to explore the joint ...
Moderate elevation of plasma total homocysteine (tHcy) is a strong and independent risk factor for c...
Elevated plasma total homocysteine (hcy), a risk factor for Coronary Artery Disease (CAD), is due to...
BACKGROUND: Moderately elevated blood levels of homocysteine are weakly correlated with coronary hea...
Background: Moderately elevated blood levels of homocysteine are weakly correlated with coronary hea...
<FONT FACE="Arial"><strong>Background</strong> Homocysteine is a sulfur-containing amino acid formed...
BACKGROUND: Moderately elevated blood levels of homocysteine are weakly correlated with coronary hea...
Background Moderately elevated blood levels of homocysteine are weakly correlated with coronary hear...