We reconstructed the late Holocene relative sea-level (RSL) evolution of the ancient harbour of Naples, one of the largestcoastal conurbations in the Mediterranean. We carried out multiproxy investigations, coupling archaeological evidencewith biological indicators. Our data robustly constrain 2000 yr of non-monotonic changes in sea level, chiefly controlledby the complex volcano-tectonic processes that characterize the area. Between∼200 BC and AD∼0, a subsidence rateof more than∼1.5 mm/yr enhanced the postglacial RSL rise, while negligible or moderate land uplift <∼0.5 mm/yr triggereda RSL stabilization during the Roman period (firstfive centuries AD). This stabilization was followed by a post-Romanenhancement of the sea-level rise when gr...