Add to ORKGFunctional inactivation of Mismatch Repair (MMR) genes by mutations or epigenetic mechanisms favors the acquisition of mutations in 'target genes'. We analysed 94 colorectal cancer (CRC) with microsatellite instability-high (MSI-H) for the presence of mutations in microsatellites located in the coding regiobns (CDRs) of 6 geens: TGF; RII, BAX, hMLH3, hMSH6, MBD4 and BLM
Microsatellite instability occurs in 15% of colorectal carcinomas and may be due to replication erro...
DNA mismatch repair deficiency is observed in about 15% of human colorectal, gastric, and endometria...
Microsatellite instability occurs in 15% of colorectal carcinomas and may be due to replication erro...
Functional inactivation of Mismatch Repair (MMR) genes by mutations or epigenetic mechanisms favors ...
Microsatellites are short tandem repeat DNA sequences of one to tetra base pairs distributed through...
Approximately 20 percent of right-sided colon cancers and 5 percent of left-sided colon and rectal c...
Defects in the mismatch repair system lead to microsatellite instability (MSI), a feature observed i...
Defects in the mismatch repair system lead to microsatellite instability (MSI), a feature observed i...
Defects in the mismatch repair system lead to microsatellite instability (MSI), a feature observed i...
Defects in the mismatch repair system lead to microsatellite instability (MSI), a feature observed i...
Microsatellite instability (MSI) results from defective DNA produced as an end result of mismatch. A...
Inactivation of the DNA mismatch repair (MMR) system would lead to an increased mutation rate and p...
Microsatellite instability (MSI) in colorectal tumours is demonstrated by PCR amplification of sever...
Although microsatellite instability (MSI) has been shown to be present in 15% of sporadic colorectal...
Colon carcinomas with microsatellite mutator phenotype exhibit specific genetic and clinico-patholog...
Microsatellite instability occurs in 15% of colorectal carcinomas and may be due to replication erro...
DNA mismatch repair deficiency is observed in about 15% of human colorectal, gastric, and endometria...
Microsatellite instability occurs in 15% of colorectal carcinomas and may be due to replication erro...
Functional inactivation of Mismatch Repair (MMR) genes by mutations or epigenetic mechanisms favors ...
Microsatellites are short tandem repeat DNA sequences of one to tetra base pairs distributed through...
Approximately 20 percent of right-sided colon cancers and 5 percent of left-sided colon and rectal c...
Defects in the mismatch repair system lead to microsatellite instability (MSI), a feature observed i...
Defects in the mismatch repair system lead to microsatellite instability (MSI), a feature observed i...
Defects in the mismatch repair system lead to microsatellite instability (MSI), a feature observed i...
Defects in the mismatch repair system lead to microsatellite instability (MSI), a feature observed i...
Microsatellite instability (MSI) results from defective DNA produced as an end result of mismatch. A...
Inactivation of the DNA mismatch repair (MMR) system would lead to an increased mutation rate and p...
Microsatellite instability (MSI) in colorectal tumours is demonstrated by PCR amplification of sever...
Although microsatellite instability (MSI) has been shown to be present in 15% of sporadic colorectal...
Colon carcinomas with microsatellite mutator phenotype exhibit specific genetic and clinico-patholog...
Microsatellite instability occurs in 15% of colorectal carcinomas and may be due to replication erro...
DNA mismatch repair deficiency is observed in about 15% of human colorectal, gastric, and endometria...
Microsatellite instability occurs in 15% of colorectal carcinomas and may be due to replication erro...