Innovative paradigms and frameworks have to be identi\ufb01ed to enable the effective deployment and execution of pervasive computing services able to enforcing properties of self-organization and self-adaptability, self-management, and of long-lasting evolvability. This paper discusses how such frameworks should get inspiration from natural systems, by enabling modeling and deployment of services as autonomous individuals, spatially-situated in a system of other services, data sources, and pervasive devices, all of which acting, interacting, and evolving according to a limited set of spatial \u201claws of nature\u201d. In this context, this paper presents a reference architecture to uniformly frame such concepts, surveys and critically ana...