While much is known about muscle spindle structure, innervation and function, relatively few factors have been identified that regulate intrafusal fiber differentiation and spindle development. Identification of these factors will be a crucial step in tissue engineering functional muscle systems. In this study, we investigated the role of the growth factor, neuregulin 1-β-1 (Nrg 1-β-1) EGF, for its ability to influence myotube fate specification in a defined culture system utilizing the non-biological substrate N-1[3-(trimethoxysilyl)propyl]-diethylenetriamine (DETA). Based on morphological and immunocytochemical criteria, Nrg 1-β-1 treatment of developing myotubes increases the ratio of nuclear bag fibers to total myotubes from 0.019 to 0....
This work describes the step-by-step development of a novel, serum-free, in vitro cell culture syste...
This work describes the step-by-step development of a novel, serum-free, in vitro cell culture syste...
This work describes the step-by-step development of a novel, serum-free, in vitro cell culture syste...
While much is known about muscle spindle structure, innervation and function, relatively few factors...
While much is known about muscle spindle structure, innervation and function, relatively few factors...
While much is known about muscle spindle structure, innervation and function, relatively few factors...
Muscle spindles are sensory organs that detect and mediate both static and dynamic muscle stretch a...
Thesis (Master's)--University of Washington, 2023Abstract: Intrafusal fibers of the muscle spindle p...
Intrafusal fibres are a specialised population in skeletal muscle, found within the muscle spindle. ...
Abstract Background The formation of intrafusal muscle (IM) fibers and their contact with afferent p...
The first descriptions of muscle spindles with intrafusal fibres containing striated myofibrils and ...
Muscle spindles are an essential part of the neuro-muscular system because they act as sensory recep...
Skeletal muscle is a complex tissue with a capacity to regenerate upon injury. However, when skeleta...
Muscle spindles are sensory organs embedded in the belly of skeletal muscles that serve as mechanore...
This work describes the step-by-step development of a novel, serum-free, in vitro cell culture syste...
This work describes the step-by-step development of a novel, serum-free, in vitro cell culture syste...
This work describes the step-by-step development of a novel, serum-free, in vitro cell culture syste...
This work describes the step-by-step development of a novel, serum-free, in vitro cell culture syste...
While much is known about muscle spindle structure, innervation and function, relatively few factors...
While much is known about muscle spindle structure, innervation and function, relatively few factors...
While much is known about muscle spindle structure, innervation and function, relatively few factors...
Muscle spindles are sensory organs that detect and mediate both static and dynamic muscle stretch a...
Thesis (Master's)--University of Washington, 2023Abstract: Intrafusal fibers of the muscle spindle p...
Intrafusal fibres are a specialised population in skeletal muscle, found within the muscle spindle. ...
Abstract Background The formation of intrafusal muscle (IM) fibers and their contact with afferent p...
The first descriptions of muscle spindles with intrafusal fibres containing striated myofibrils and ...
Muscle spindles are an essential part of the neuro-muscular system because they act as sensory recep...
Skeletal muscle is a complex tissue with a capacity to regenerate upon injury. However, when skeleta...
Muscle spindles are sensory organs embedded in the belly of skeletal muscles that serve as mechanore...
This work describes the step-by-step development of a novel, serum-free, in vitro cell culture syste...
This work describes the step-by-step development of a novel, serum-free, in vitro cell culture syste...
This work describes the step-by-step development of a novel, serum-free, in vitro cell culture syste...
This work describes the step-by-step development of a novel, serum-free, in vitro cell culture syste...