Lymph nodes (LNs) aid the interaction between lymphocytes and antigen-presenting cells, resulting in adequate and prolonged adaptive immune responses. LN stromal cells (LNSCs) are crucially involved in steering adaptive immune responses at different levels. Most knowledge on LNSCs has been obtained from mouse studies, and few studies indicate similarities with their human counterparts. Recent advances in single-cell technologies have revealed significant LNSC heterogeneity among different subsets with potential selective functions in immunity. This review provides an overview of current knowledge of LNSCs based on human and murine studies describing the role of these cells in health and disease
Lymph nodes (LNs) are highly organized secondary lymphoid organs that mediate adaptive immune respon...
Stromal cells (SCs) establish the compartmentalization of lymphoid tissues critical to the immune re...
Lymphocytes constantly survey the lymph nodes in search for potential infection by a pathogen. They ...
Lymph nodes (LNs) aid the interaction between lymphocytes and antigen-presenting cells, resulting in...
Secondary lymphoid organs are critical for efficient interaction between innate antigen presenting c...
Lymph node stromal cells (LNSCs) closely regulate immunity and self-tolerance, yet key aspects of th...
Secondary lymphoid organs (SLOs), including lymph nodes, Peyer's patches, and the spleen, have evolv...
Antigen presentation is no longer the exclusive domain of cells of hematopoietic origin. Recent work...
Lymph node stromal cells coordinate the adaptive immune response in secondary lymphoid organs, provi...
Secondary lymphoid organs (SLO), including the spleen and lymph nodes (LN) are a meeting place for i...
International audienceLymphoid stromal cells are best known as the architectural cells of lymphoid o...
Adaptive immunity critically depends on the functional compartmentalization of secondary lymphoid or...
Lymph nodes (LNs) are distributed all over the body and whatever the site consists of the same cell ...
Lymph node stromal cells (LNSCs) shape the lymph nodes (LNs), where adaptive immune responses are in...
Stromal cells (SCs) establish the compartmentalization of lymphoid tissues critical to the immune re...
Lymph nodes (LNs) are highly organized secondary lymphoid organs that mediate adaptive immune respon...
Stromal cells (SCs) establish the compartmentalization of lymphoid tissues critical to the immune re...
Lymphocytes constantly survey the lymph nodes in search for potential infection by a pathogen. They ...
Lymph nodes (LNs) aid the interaction between lymphocytes and antigen-presenting cells, resulting in...
Secondary lymphoid organs are critical for efficient interaction between innate antigen presenting c...
Lymph node stromal cells (LNSCs) closely regulate immunity and self-tolerance, yet key aspects of th...
Secondary lymphoid organs (SLOs), including lymph nodes, Peyer's patches, and the spleen, have evolv...
Antigen presentation is no longer the exclusive domain of cells of hematopoietic origin. Recent work...
Lymph node stromal cells coordinate the adaptive immune response in secondary lymphoid organs, provi...
Secondary lymphoid organs (SLO), including the spleen and lymph nodes (LN) are a meeting place for i...
International audienceLymphoid stromal cells are best known as the architectural cells of lymphoid o...
Adaptive immunity critically depends on the functional compartmentalization of secondary lymphoid or...
Lymph nodes (LNs) are distributed all over the body and whatever the site consists of the same cell ...
Lymph node stromal cells (LNSCs) shape the lymph nodes (LNs), where adaptive immune responses are in...
Stromal cells (SCs) establish the compartmentalization of lymphoid tissues critical to the immune re...
Lymph nodes (LNs) are highly organized secondary lymphoid organs that mediate adaptive immune respon...
Stromal cells (SCs) establish the compartmentalization of lymphoid tissues critical to the immune re...
Lymphocytes constantly survey the lymph nodes in search for potential infection by a pathogen. They ...