Phytochemistry of Ziziphus Mauritiana; its Antioxidant and Antimicrobial Potential

Background: Z. mauritiana is a very common and easily available plant all over the world, including Pakistan. It finds a lot of importance due to its nutritional and medicinal value.Methods: Current studies were performed to investigate the phytochemical nature and antioxidant and antimicrobial potential of Z. mauritiana (Lahore, Pakistan). Total phenolic contents in leaves and pulp extracts were identified using a modified Folin-Ciocalteu’s method while total sugars were determined by Lane and Eynon method. Antioxidant activity was determined by DPPH radical-scavenging activity assay using a UV-Visible spectrophotometer at 517 nm. The antimicrobial potential was tested by agar well diffusion method using imipenem as standard drug.Results: The methanolic extracts of leaves and pulp contained tannins, saponins, phlobatannins, alkaloids and flavonoids while steroids were absent in both the samples. The pulp and leave extracts have shown the presence of 57.3% and 37.89% sugar contents, respectively. The concertation of total phenolic contents (TPC) was found higher in pulp extracts as compared to that observed in leaves. The methanolic pulp extract has shown higher antioxidant potential as compared to the leaves extract. However, methanolic leaves extract exhibited higher antibacterial potential as compared to the methanolic pulp extract.Conclusion: The methanolic extracts of Z. Mauritiana pulp and leaves contain many biologically active ingredients and are biologically active against most of the tested bacterial strains. Its pulp and leaves are richer in numerous antioxidants and secondary metabolites. The pulp extract exhibited higher antioxidant potential as compared to the leaves extract.Keywords: Z. Mauritiana; Phytochemicals; Total Phenolic contents; Antibacterial