Collagen meniscus implant (CMI) was performed on 50 patients, who were affected by irreparable meniscal lesions or had previously undergone partial medial meniscectomy. Additional procedures included 16 ACL reconstruction, 8 high tibial osteotomy and 2 autologous chondrocyte implantation. All knees were evaluated according to the Lysholm II and Tegner activity scales. MRI was performed 6, 12 and 24 months postoperatively. Follow up averaged 15.7 (6-31) months. At most recent evaluation, 46 patients showed improvement of the clinical scores. MRI was useful to document tissue invasion and ingrowth inside the scaffold: a progression toward a more homogeneous signal was detected in the implants with a two-year follow-up. Clinical results achiev...