This dissertation concerns the content and structure of eight interventions that appear to be effective for families with multiple and complex problems (FMP): which elements do these interventions consist of and which elements are helpful to FMP? It appears that the interventions differ hardly in terms of content and are equally effective. Many elements, such as learning parents parenting skills, are addressed in all interventions, but there are also elements that only occur in a part of the interventions or are hardly applied in practice. Parents and adolescents indicate that exactly these elements, such as activating the social network or focusing on the underlying cause of behavior, are helpful to them. Furthermore, the eight interventio...