Immunotherapy treatment with checkpoint inhibitors (CPI) (CTLA-4 and PD-1 inhibitors) significantly improves survival in a number of cancers. Treatment can be limited by immune-mediated adverse effects including endocrinopathies such as hypophysitis, adrenalitis, thyroiditis and diabetes mellitus. If endocrinopathies (particularly hypocortisolemia) are not recognized early, they can be fatal. The diagnosis and management of endocrinopathies can be complicated by simultaneous multi-organ immune adverse effects. Here, we present Endocrine Emergency Guidance for the acute management of the endocrine complications of checkpoint inhibitor therapy, the first specialty-specific guidance with Endocrinology, Oncology and Acute Medicine input and end...
Immune checkpoint inhibitors block the checkpoint molecules. Different types of cancer immune checkp...
Immune checkpoint inhibitors are a new and effective class of cancer therapy, with ipilimumab being ...
Immunotherapy using monoclonal antibodies — checkpoint inhibitors — is a dynamically evolving discip...
Immunotherapy treatment with checkpoint inhibitors (CPI) (CTLA-4 and PD-1 inhibitors) significantly ...
Immunotherapy treatment with checkpoint inhibitors (CPI) (CTLA-4 and PD-1 inhibitors) significantly ...
The management of cancer patients has changed due to the considerably more frequent use of immune ch...
Three mAbs targeting immune checkpoint proteins are available for the treatment of patients with mel...
Recently immune checkpoint inhibitors amazingly changed the landscape of cancer therapy worldwide. T...
Immune checkpoint inhibitors (ICI) have revolutionized cancer treatment but are associated with sign...
Immune checkpoint inhibitors (ICIs) have revolutionized the therapeutic landscape of solid tumors. H...
Immune checkpoint inhibitors (ICIs) have been approved for the treatment of many cancers, either in ...
Anticancer immunotherapy, in the form of immune checkpoint inhibition, is a paradigm shift that has ...
AbstractImmune checkpoint inhibition against advance malignancies was named breakthrough discovery b...
Immune checkpoints are small molecules produced by immune cells that play crucial role in maintainin...
Side effects of immune checkpoint blockade are often said to be infrequent and usually mild. The uni...
Immune checkpoint inhibitors block the checkpoint molecules. Different types of cancer immune checkp...
Immune checkpoint inhibitors are a new and effective class of cancer therapy, with ipilimumab being ...
Immunotherapy using monoclonal antibodies — checkpoint inhibitors — is a dynamically evolving discip...
Immunotherapy treatment with checkpoint inhibitors (CPI) (CTLA-4 and PD-1 inhibitors) significantly ...
Immunotherapy treatment with checkpoint inhibitors (CPI) (CTLA-4 and PD-1 inhibitors) significantly ...
The management of cancer patients has changed due to the considerably more frequent use of immune ch...
Three mAbs targeting immune checkpoint proteins are available for the treatment of patients with mel...
Recently immune checkpoint inhibitors amazingly changed the landscape of cancer therapy worldwide. T...
Immune checkpoint inhibitors (ICI) have revolutionized cancer treatment but are associated with sign...
Immune checkpoint inhibitors (ICIs) have revolutionized the therapeutic landscape of solid tumors. H...
Immune checkpoint inhibitors (ICIs) have been approved for the treatment of many cancers, either in ...
Anticancer immunotherapy, in the form of immune checkpoint inhibition, is a paradigm shift that has ...
AbstractImmune checkpoint inhibition against advance malignancies was named breakthrough discovery b...
Immune checkpoints are small molecules produced by immune cells that play crucial role in maintainin...
Side effects of immune checkpoint blockade are often said to be infrequent and usually mild. The uni...
Immune checkpoint inhibitors block the checkpoint molecules. Different types of cancer immune checkp...
Immune checkpoint inhibitors are a new and effective class of cancer therapy, with ipilimumab being ...
Immunotherapy using monoclonal antibodies — checkpoint inhibitors — is a dynamically evolving discip...