The concept of spectral relative entropy rate is introduced for jointly stationary Gaussian processes. Using classical information-theoretic results, we establish a remarkable connection between time and spectral domain relative entropy rates. This naturally leads to a new spectral estimation technique where a multivariate version of the Itakura–Saito distance is employed. It may be viewed as an extension of the approach, called THREE, introduced by Byrnes, Georgiou, and Lindquist in 2000 which, in turn, followed in the footsteps of the Burg–Jaynes Maximum Entropy Method. Spectral estimation is here recast in the form of a constrained spectrum approximation problem where the distance is equal to the processes relative entropy rate. The corr...