Selection of proliferation markers for calculating pseudo-proliferation index in proteomics and transcriptomics data.

Volcano plots showing the mean correlation of proteins (a) or transcripts (b) to growth rates in the NCI60 data sets (horizontal axis) and the -log10(coefficient of variance) across all the data sets (vertical axis). Proteins quantified in less than 3 data sets were excluded in (a). Proteins/genes of interest are highlighted, and proliferation markers identified from literature search are indicated with triangles. These were color coded based of their expression peak according to Santos et al. [17]. (TIFF)