Precision measures of electroweak and flavour observables, at both low and high energies, are highly complementary to direct searches for New Physics at high-energy colliders. Despite the discovery of the Higgs boson at the Large Hadron Collider, and of the overwhelming successes of the Standard Model, several observational and theoretical problems remain to be addressed. In addition to neutrino oscillation phenomena, the Standard Model fails to explain the baryon asymmetry of the Universe, and does not offer a viable dark matter candidate. In recent years, numerous deviations between the Standard Model prediction and experimental measurements have been identified; interestingly, most are closely connected to lepton flavours.In this thesis ...