A: CpGs sites analyzed in the HbSS group. i cg03949391-PTGFR; ii cg3989617-GPR56; iii cg0727418-GALR2 and iv cg23179456-ADCY4. B: CpGs sites analyzed in the HbSC group. i cg24847829-SPOCK1; ii cg24676244-THSD7A and iii cg23179456-ADCY. *p<0.05, **p<0.01 (Student’s unpaired t test).</p
<p>*—<i>target CpG site</i>.</p><p><sup>ψ —</sup>control values are from the previous study [<a href...
<p>Methylation level of GR exon 1F at individual CpG sites for females (n = 46) (2A) and males (n = ...
<p>DNA methylation for 1027 CpG sites was assessed in AECs compared to PBMCs from all subjects. A. V...
The underlined CpGs are these selected from NGS, while the nonunderlined CpGs are the adjacent to th...
<p>Validation of significant methylation differences identified by microarray (450 K) by pyrosequenc...
A: Analysis in the HbSS group. i PTGFR; ii GPR56; iii GALR2 and iv ADCY4. B: Analysis in the HbSC gr...
<p>A. Schematic diagram of the CpG island within <i>p15<sup>INK4b</sup></i>. Seven CpG sites detecte...
<p>DNA methylation [%] determined by pyrosequencing at five consecutive CpG sites in the <i>MEST</i>...
<p>Average methylation level of CpG sites within promoters of TABPB and ZBTB18 were assessed using p...
<p>A. An exemplary pyrogram showing the methylation level in each analysed CpG between the represent...
<p>A fifth CpG site is preceded by a 7 base pair T stretch (after bisulfite conversion), making it i...
<p>(<b>A</b>) Sequence of PCR amplified 287 bp fragment of differentially methylated region 2 (DMR2)...
<p>A) CpG methylation of promoter regions of selected genes analysed by MeDIP. B) CpG methylation of...
<p>Methylation values at the CpG sites of interest in <i>LARS2</i> and <i>IRAK2</i> determined by bi...
<p>PCR products obtained from three independent bisulfite treated DNA of female BPD patients (n=9) a...
<p>*—<i>target CpG site</i>.</p><p><sup>ψ —</sup>control values are from the previous study [<a href...
<p>Methylation level of GR exon 1F at individual CpG sites for females (n = 46) (2A) and males (n = ...
<p>DNA methylation for 1027 CpG sites was assessed in AECs compared to PBMCs from all subjects. A. V...
The underlined CpGs are these selected from NGS, while the nonunderlined CpGs are the adjacent to th...
<p>Validation of significant methylation differences identified by microarray (450 K) by pyrosequenc...
A: Analysis in the HbSS group. i PTGFR; ii GPR56; iii GALR2 and iv ADCY4. B: Analysis in the HbSC gr...
<p>A. Schematic diagram of the CpG island within <i>p15<sup>INK4b</sup></i>. Seven CpG sites detecte...
<p>DNA methylation [%] determined by pyrosequencing at five consecutive CpG sites in the <i>MEST</i>...
<p>Average methylation level of CpG sites within promoters of TABPB and ZBTB18 were assessed using p...
<p>A. An exemplary pyrogram showing the methylation level in each analysed CpG between the represent...
<p>A fifth CpG site is preceded by a 7 base pair T stretch (after bisulfite conversion), making it i...
<p>(<b>A</b>) Sequence of PCR amplified 287 bp fragment of differentially methylated region 2 (DMR2)...
<p>A) CpG methylation of promoter regions of selected genes analysed by MeDIP. B) CpG methylation of...
<p>Methylation values at the CpG sites of interest in <i>LARS2</i> and <i>IRAK2</i> determined by bi...
<p>PCR products obtained from three independent bisulfite treated DNA of female BPD patients (n=9) a...
<p>*—<i>target CpG site</i>.</p><p><sup>ψ —</sup>control values are from the previous study [<a href...
<p>Methylation level of GR exon 1F at individual CpG sites for females (n = 46) (2A) and males (n = ...
<p>DNA methylation for 1027 CpG sites was assessed in AECs compared to PBMCs from all subjects. A. V...