Adult <i>Rbm46</i><sup>-/-</sup> testes contained abundant Sertoli cells but lacked SYCP3+ meiotic spermatocytes.
- Natoya J. Peart (13840420)
- Taylor A. Johnson (13840423)
- Sungkyoung Lee (11286780)
- Matthew J. Sears (13840426)
- Fang Yang (123514)
- Mathieu Quesnel-Vallières (6995189)
- Huijuan Feng (5451185)
- Yocelyn Recinos (5628695)
- Yoseph Barash (48182)
- Chaolin Zhang (28120)
- Brian P. Hermann (13840429)
- P. Jeremy Wang (10204629)
- Christopher B. Geyer (13840432)
- Russ P. Carstens (13840435)
Publication date
September 2022
DOI Publisher
Public Library of Science (PLoS)Abstract
(A-B) GATA4+ Sertoli cells (green) were present in both Rbm46+/- and Rbm46-/- testes, but there were few TRA98+ (red) germ cells in Rbm46-/- testes. (C-D) In contrast to Rbm46+/- testes, there were no SYCP3+ (green) spermatocytes in Rbm46-/- testes. (E-F) Using Rbm46+/- and Rbm46-/- testes, the numbers of germ cells (E) and % cell fate (F) were quantified. Nuclei were stained with DAPI (blue). Scale bar = 50 μm. (TIF)</p
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