Conditional deletion of <i>Rbm46</i> with <i>Stra8</i>-Cre resulted in an adult spermatogenesis phenotype resembling that of whole-body KO mice.
- Natoya J. Peart (13840420)
- Taylor A. Johnson (13840423)
- Sungkyoung Lee (11286780)
- Matthew J. Sears (13840426)
- Fang Yang (123514)
- Mathieu Quesnel-Vallières (6995189)
- Huijuan Feng (5451185)
- Yocelyn Recinos (5628695)
- Yoseph Barash (48182)
- Chaolin Zhang (28120)
- Brian P. Hermann (13840429)
- P. Jeremy Wang (10204629)
- Christopher B. Geyer (13840432)
- Russ P. Carstens (13840435)
Publication date
September 2022
DOI Publisher
Public Library of Science (PLoS)Abstract
(A-C) Compared to controls, adult conditional KO testes were dramatically reduced in size. (D) Seminiferous epithelia from control mice (left panel) contained Sertoli cells as well as all advanced germ cell types, with examples marked including leptotene (Lep) and pachytene (Pac) spermatocytes as well as elongated spermatids (ES). In stark contrast, seminiferous epithelia of conditional KO testes contained only somatic Sertoli cells and a few spermatogonia (Spg). Scale bar = 50 μm. (TIF)</p
Add to ORKG