(A) Model showing various potential protein molecules (red labels) involved in generating and/or sensing the cellular tension. (B) Quantification of DNMT3a localization (nuclear v/s cytoplasmic) in EGTA and blebbistatin-treated keratinocytes compared to control (n = 3). (C) Quantification of DNMT3a localization in scratch wound proximal (≤100 μm) keratinocytes comparing control and calyculin-A-treated scratch wounds (n = 3). (D) Quantification of DNMT3a localization in (n = 3). (Data are shown as mean ± SEM, P-values were calculated using 2-tailed t test (D), * P ≤ 0.05, ** P ≤ 0.01, *** P ≤ 0.001, ns = P > 0.05.) Data underlying the graphs can be found in S4B–S4D Fig of S1 Raw Data. (TIF)</p
Transforming Growth Factor (TGF-beta1) is a member of the TGF-beta superfamily ligand-receptor netwo...
Dermal wound repair involves complex interactions between cells, cytokines and mechanics to close in...
<p>(A-B) WT and DP-null keratinocytes stained for E-cadherin (green) and α-catenin (red) after 24 h ...
(A) DNMT3a and DAPI staining of wound proximal (B) Quantification and kinetics of DNMT3a localizati...
(A) Representative image of unwounded/wound-distal skin section stained with DNMT3a, DAPI, and K5. (...
(A) Effect of EGTA and blebbistatin on the localization of DNMT3a. (B) Effect of scratch wound DNMT3...
(A) qPCR analysis of caspase-8 mRNA in scratch wounded keratinocytes, pre-treated with 5-Aza-2′-deox...
In vivo and in vitro studies give a paradoxical picture of the actions of the key regulatory factor ...
<p>(<b>A, B</b>) TGF-β1, (<b>C, D</b>) TGF-β2, and (<b>E, F</b>) TGF-β3. RNA expression is normalize...
(A) ChIP-qPCR analysis to check DNMT3a and DNMT3b occupancy at caspase-8 promoter in control and scr...
<p>(<b>A, B</b>) TβRI, (<b>C, D</b>) TβRII, and (<b>E, F</b>) TβRIII. RNA expression is normalized t...
In vivo and in vitro studies give a paradoxical picture of the actions of the key regulatory factor ...
The skin forms an efficient barrier against the environment, and rapid cutaneous wound healing after...
Re-epithelialization is the dominant mode of healing in partial thickness wounds. In order to develo...
The epidermis is the outermost layer of skin and consists mainly of keratinocytes that form a strati...
Transforming Growth Factor (TGF-beta1) is a member of the TGF-beta superfamily ligand-receptor netwo...
Dermal wound repair involves complex interactions between cells, cytokines and mechanics to close in...
<p>(A-B) WT and DP-null keratinocytes stained for E-cadherin (green) and α-catenin (red) after 24 h ...
(A) DNMT3a and DAPI staining of wound proximal (B) Quantification and kinetics of DNMT3a localizati...
(A) Representative image of unwounded/wound-distal skin section stained with DNMT3a, DAPI, and K5. (...
(A) Effect of EGTA and blebbistatin on the localization of DNMT3a. (B) Effect of scratch wound DNMT3...
(A) qPCR analysis of caspase-8 mRNA in scratch wounded keratinocytes, pre-treated with 5-Aza-2′-deox...
In vivo and in vitro studies give a paradoxical picture of the actions of the key regulatory factor ...
<p>(<b>A, B</b>) TGF-β1, (<b>C, D</b>) TGF-β2, and (<b>E, F</b>) TGF-β3. RNA expression is normalize...
(A) ChIP-qPCR analysis to check DNMT3a and DNMT3b occupancy at caspase-8 promoter in control and scr...
<p>(<b>A, B</b>) TβRI, (<b>C, D</b>) TβRII, and (<b>E, F</b>) TβRIII. RNA expression is normalized t...
In vivo and in vitro studies give a paradoxical picture of the actions of the key regulatory factor ...
The skin forms an efficient barrier against the environment, and rapid cutaneous wound healing after...
Re-epithelialization is the dominant mode of healing in partial thickness wounds. In order to develo...
The epidermis is the outermost layer of skin and consists mainly of keratinocytes that form a strati...
Transforming Growth Factor (TGF-beta1) is a member of the TGF-beta superfamily ligand-receptor netwo...
Dermal wound repair involves complex interactions between cells, cytokines and mechanics to close in...
<p>(A-B) WT and DP-null keratinocytes stained for E-cadherin (green) and α-catenin (red) after 24 h ...