Vim −/− mice are smaller than WT.

(a) Body weight of WT and Vim −/− male mice of 3 (n = 6) and 6 months old (n = 4). (b) BMI and (c) Lee’s indexes were calculated for 6 months old mice (n = 8). (d) Total fat mass determined by EcoMRI and ratio of fat/weight of 6 months old male mice (n = 7–8). (e) Micrograph of adipocytes from 3 months old WT and Vim −/− male mice. The size of retroperitoneal and perigonadal adipocytes were quantified using Fiji (n = 3, 250 cells in total). (f) Organ weight of kidney (n = 6) and heart (n = 3) from 3 months old male mice. The results are presented in the form of mean ± standard deviation of the mean of the biological replicates. Scale bar = 100 μm, *p p p p S1 Data.