Allogeneic IBM-SCT reduced acute GVHD compared to IV-SCT in the FVB/N-Tg into BALB/c mouse model.
- Yoshiko Yamasuji-Maeda (13767344)
- Hisakazu Nishimori (13767347)
- Keisuke Seike (13767350)
- Akira Yamamoto (560236)
- Hideaki Fujiwara (6056186)
- Taiga Kuroi (13767353)
- Kyosuke Saeki (13767356)
- Haruko Fujinaga (13767359)
- Sachiyo Okamoto (13767362)
- Ken-ichi Matsuoka (2311861)
- Nobuharu Fujii (219190)
- Takehiro Tanaka (7374551)
- Masahiro Fujii (2168368)
- Katsumi Mominoki (13767365)
- Takuro Kanekura (278777)
- Yoshinobu Maeda (441679)
Publication date
September 2022
DOI Publisher
Public Library of Science (PLoS)Abstract
Lethally (9-Gy-split dose) irradiated BALB/c mice were transplanted with 2 × 106 FVB/N-Tg spleen T cells and 5 × 106 FVB/N-Tg BM cells. The recipients were analyzed in terms of survival (A), body weight change (B), and acute GVHD score after SCT (C) (Syn IV, n = 10; Syn IBM, n = 10; Allo IV, n = 10; Allo IBM, n = 10). Data from two independent experiments were combined. *P n = 10; Allo IBM, n = 10). Data from two independent experiments were combined. *P (TIF)</p
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