Gold Nanoclusters: Imaging, Therapy, and Theranostic Roles in Biomedical Applications

van de Looij, Sanne M.
Hebels, Erik R.
Viola, Martina
Hembury, Mathew
Oliveira, Sabrina
Vermonden, Tina

Publication date

January 2022

Abstract

For the past two decades, atomic gold nanoclusters (AuNCs, ultrasmall clusters of several to 100 gold atoms, having a total diameter of <2 nm) have emerged as promising agents in the diagnosis and treatment of cancer. Owing to their small size, significant quantization occurs to their conduction band, which leads to emergent photonic properties and the disappearance of the plasmonic responses observed in larger gold nanoparticles. For example, AuNCs exhibit native luminescent properties, which have been well-explored in the literature. Using proteins, peptides, or other biomolecules as structural scaffolds or capping ligands, required for the stabilization of AuNCs, improves their biocompatibility, while retaining their distinct optical pro...

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Gold Nanoclusters: Imaging, Therapy, and Theranostic Roles in Biomedical Applications

Abstract

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Gold Nanoclusters: Imaging, Therapy, and Theranostic Roles in Biomedical Applications

Abstract

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