Analysis of infection therapy in paediatric department I.

Analysis of infection therapy in paediatric department I Author: Tomáš Trávníček Tutor: doc. PharmDr. Josef Malý, Ph.D. Consultant: MUDr. Magdalena Rohanová, Mgr. Petr Domecký Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: Infections in newborns are one of the most frequent causes of death. The aim of this work was the retrospective analysis of bacterial infection in newborns with a birth weight ≤ 1500 g hospitalized in Paediatric Intensive Care Unit (ICU) and compare it with the latest findings published in the expect literature. Methods: The retrospective cross-sectional study took place in Paediatric ICU. The data were gathered between 07/29 and 08/10 2020. The study included patients in neonatal age with a birth weight ≤ 1500 g hospitalized in the Paediatric ICU in 2018 and 2019 with bacterial infection. The infection was proved by a positive cultivation, increased C-reactive protein and increased or reduced number of white blood cells. Information on the patient, infectious agent, laboratory tests, occurrence of risk factors for sepsis, selection of antibiotics, its susceptibility, dose, dosing interval and duration of administration, as well as the result of therapy were collected to a prepared form. The data were..