International audienceDevelopments of new radioactive beams and thus of new target-ion-sources (TIS) for isotopeseparator- on-line (ISOL) production systems are in progress at GANIL for the SPIRAL 2 project. Measurements of the time response and of the efficiency of each step of the production process are crucial to predict the available yields, in particular for short lived isotopes. This paper presents a method that uses a chopped beam of stable alkali of controlled intensity. This method was applied on SISTHE (Source à Ionisation de Surface de Test à Haute Efficacité). During the tests, the ionization efficiency is extracted from the ratio between the flux emerging from the TIS and the flux implanted in the TIS. Time responses are obtain...