International audienceA promising synthetic route towards bioactive guaianolide sesquiterpene lactones is presented. The strategy is based on a recently invented multicomponent reaction (MARDi cascade) and subsequent highly chemoselective and domino transformations for the expeditious stereoselective preparation of the tricyclic core of the natural products
Synthetic efforts towards various meroterpenoid natural products based on biosynthetic speculation w...
Studies aimed at a comparison of chemical, biomimetic (Gif system GoAggIII)and enzymatic (CHMO) tran...
The aim of this work was to seek for the first synthetic route towards Cynaropicrin and Ixerin Y, tw...
International audienceA promising synthetic route towards bioactive guaianolide sesquiterpene lacton...
Guaianolides, known as biologically important hydroazulenic sesquiterpene lactones, have so far only...
Guaianolides constitute a large and diverse group of biologically active sesquiterpenes. Guaianolide...
Guaianolides consisting of tricyclic 5,7,5-ring system represents one of the largest subgroup of nat...
The main thread throughout this thesis is to develop reaction sequences that could provide facile ac...
Guaianolides, the largest class of sesquiterpene lactones, possess a wide range of biological activi...
Cette thèse développe de nouvelles séquences réactionnelles divergentes vers les lactones sesquiterp...
Natural selection: An acyclic chain containing an ene-yne-ene motif, in analogy to farnesyl diphosph...
Sesquiterpene lactones are secondary metabolites mainly found in the Asteraceae family. These compou...
A study on the electrophile-induced rearrangement of two 15-hydroxygermacranolides, salonitenolide a...
In this highlight we describe two case studies from our laboratory, involving the biomimetic synthes...
Sesquiterpenes have been a rich source of bioactive compounds and have inspired innovative methodolo...
Synthetic efforts towards various meroterpenoid natural products based on biosynthetic speculation w...
Studies aimed at a comparison of chemical, biomimetic (Gif system GoAggIII)and enzymatic (CHMO) tran...
The aim of this work was to seek for the first synthetic route towards Cynaropicrin and Ixerin Y, tw...
International audienceA promising synthetic route towards bioactive guaianolide sesquiterpene lacton...
Guaianolides, known as biologically important hydroazulenic sesquiterpene lactones, have so far only...
Guaianolides constitute a large and diverse group of biologically active sesquiterpenes. Guaianolide...
Guaianolides consisting of tricyclic 5,7,5-ring system represents one of the largest subgroup of nat...
The main thread throughout this thesis is to develop reaction sequences that could provide facile ac...
Guaianolides, the largest class of sesquiterpene lactones, possess a wide range of biological activi...
Cette thèse développe de nouvelles séquences réactionnelles divergentes vers les lactones sesquiterp...
Natural selection: An acyclic chain containing an ene-yne-ene motif, in analogy to farnesyl diphosph...
Sesquiterpene lactones are secondary metabolites mainly found in the Asteraceae family. These compou...
A study on the electrophile-induced rearrangement of two 15-hydroxygermacranolides, salonitenolide a...
In this highlight we describe two case studies from our laboratory, involving the biomimetic synthes...
Sesquiterpenes have been a rich source of bioactive compounds and have inspired innovative methodolo...
Synthetic efforts towards various meroterpenoid natural products based on biosynthetic speculation w...
Studies aimed at a comparison of chemical, biomimetic (Gif system GoAggIII)and enzymatic (CHMO) tran...
The aim of this work was to seek for the first synthetic route towards Cynaropicrin and Ixerin Y, tw...