Background: In patients with squamous cell carcinoma of the oral tongue (OTSCC), current tumor node metastasis staging system fails to identify at-risk patients associated with early relapse and poor prognosis despite complete surgical resection. Given the importance of tumor-infiltrating lymphocytes (TILs) in the development of cancers, here we investigated the prognostic significance of the immune phenotype in OTSCC. Methods: Hematoxylin-eosin stained sections of OTSCCs from 211 patients were evaluated. Cancers were classified as (a) immune-inflamed when TILs were found next to tumor cell nests; (b) immune-excluded when TILs were found in the stroma, outside the tumor; and (c) immune-desert for tumors lacking lymphocyte infiltrate. The pr...
Background:We aimed to investigate the prognostic value of tumour-infiltrating lymphocytes' (TILs) e...
Background - The majority of oral cavity cancers arise in the oral tongue. The aim of this study was...
Oral cavity squamous cell carcinoma (OSCC) is a common head and neck cancer characterized by a poor ...
Background: In patients with squamous cell carcinoma of the oral tongue (OTSCC), current tumor node ...
Abstract Tumor-infiltrating lymphocytes (TILs) have shown a promising prognostic value in many epit...
Abstract Although patients with early-stage oral tongue squamous cell carcinoma (OTSCC) show better...
Background: Cancer of the oral cavity is a common malignancy, notably in low-middle income countries...
Abstract Background Our aim was to investigate the prognostic significance of tumor-infiltrating lym...
Abstract Background Prognostic factors aid in the stratification and treatment of cancer. This study...
Although patients with early-stage oral tongue squamous cell carcinoma (OTSCC) show better survival ...
The tumor immune microenvironment is emerging as a critical player in predicting cancer prognosis an...
Background - Various immune cells have been suggested as prognostic markers for cancer patients. In ...
Metastasis is the most deadly event in cancer progression, but the cells which initiate a metastasis...
In oral-cancer, the number of tumor-infiltrating lymphocytes (TILs) associates with improved surviva...
Tumor-infiltrating lymphocytes (TILs) have shown a promising prognostic value in many epithelial can...
Background:We aimed to investigate the prognostic value of tumour-infiltrating lymphocytes' (TILs) e...
Background - The majority of oral cavity cancers arise in the oral tongue. The aim of this study was...
Oral cavity squamous cell carcinoma (OSCC) is a common head and neck cancer characterized by a poor ...
Background: In patients with squamous cell carcinoma of the oral tongue (OTSCC), current tumor node ...
Abstract Tumor-infiltrating lymphocytes (TILs) have shown a promising prognostic value in many epit...
Abstract Although patients with early-stage oral tongue squamous cell carcinoma (OTSCC) show better...
Background: Cancer of the oral cavity is a common malignancy, notably in low-middle income countries...
Abstract Background Our aim was to investigate the prognostic significance of tumor-infiltrating lym...
Abstract Background Prognostic factors aid in the stratification and treatment of cancer. This study...
Although patients with early-stage oral tongue squamous cell carcinoma (OTSCC) show better survival ...
The tumor immune microenvironment is emerging as a critical player in predicting cancer prognosis an...
Background - Various immune cells have been suggested as prognostic markers for cancer patients. In ...
Metastasis is the most deadly event in cancer progression, but the cells which initiate a metastasis...
In oral-cancer, the number of tumor-infiltrating lymphocytes (TILs) associates with improved surviva...
Tumor-infiltrating lymphocytes (TILs) have shown a promising prognostic value in many epithelial can...
Background:We aimed to investigate the prognostic value of tumour-infiltrating lymphocytes' (TILs) e...
Background - The majority of oral cavity cancers arise in the oral tongue. The aim of this study was...
Oral cavity squamous cell carcinoma (OSCC) is a common head and neck cancer characterized by a poor ...