The threat of bioterrorism, long ignored and denied, has heightened over the past few years. The terrorist attacks of September 11 and the subsequent assaults with anthrax through the postal system underscored both strengths and weakness in the U.S. public health system and sounded a warning to global health. Globally, two candidate agents are of special concern: smallpox and anthrax. The magnitude of the problems and the gravity of the scenarios associated with release of these organisms have been vividly portrayed by two epidemics of smallpox in Europe during the 1970s and by an accidental release f aerosolized anthrax from a Russian bioweapons facility in 1979. This course will address the protection of the global public health from biol...