We explore how knowledge-based connections to domestic and foreign locations affect the technological scope of firm innovations. Inspired by a blend of Economic Geography and International Business perspectives, we propose a theoretical framework that distinguishes between domestic subnational differences and cross-national spatial heterogeneity. Further, we combine the Penrosean view of managerial capabilities with the attention-based theory of the firm. Analyzing a sample of US-based firms between 1990 and 2006, we show that both domestic and international knowledge connectedness affect the technological scope of firm innovations, but their effects are different. The breadth of international knowledge connectedness appears ...