Add to ORKGPoor prescribing is a common occurrence, notably relevant in settings with at-risk patients. Patients with multiple comorbidities require multiple drug therapies, establishing fertile soil for the manifestation of adverse drug events. As organ function decreases in older patients, drug doses oftentimes are failed to be prescribed at an appropriate level. The combination of elevated doses and unnecessary prescriptions puts endangered patients at further risk for developing avoidable adverse events. In order to protect vulnerable patients, strides must be taken towards appropriate prescribing and dosing. When the focus of treatment is clear with defined goals, we can aim at providing a suitable regimen which adds life to the remaining years o...