From oils associated with the toxic syndrome have been isolated 3-phenylamino-1,2-aminophenol (PAP) and diesters with fatty acids in addition to fatty anilides. These substances have been obtained by chemical synthesis and administered orally to rats whose lymphatic canal had previously been cannulated. The lipid fraction of the lymph collected at different time intervals was isolated. Its chromatographic study has confirmed the presence of the mentioned substances, as well as a metabolite of them, demonstrating that these products enter the blood by lymphatic absorption
A technique for collection of intestinal lymph in non-restrained rats has been developed. The lymph ...
Oil and emulsion vehicles have been shown to alter the oral absorption of many drugs. This may be du...
The triglyceride (TG) mimetic prodrug (1,3-dipalmitoyl-2-mycophenoloyl glycerol, 2-MPA-TG) biochemic...
[EN]: Some compounds, other than fatty anilides, which had been isolated from oil samples involved i...
Many lipophilic compounds are absorbed to some degree via the lymphatics, however, the mechanisms an...
The retinoids are highly lipophilic molecules and are known to be transported in the intestinal lymp...
[3H]Arachidonic (20:4) and [14C]linoleic acid (18:2) were fed to thoracic duct-cannulated rats in te...
The purpose of this study was to measure the pharmacokinetics and tissue accumulation of N-acetylami...
Drugs are commonly administered via the intraperitoneal (IP) route to treat localized infections and...
The lymphatic system plays a number of roles in key physiological and pathological events, including...
The plasma-lymphatic distribution of ribonuclease (RNase), superoxide dismutase (SODase), and catala...
Liver Physiol. 2): GMLG353, 1980. The effect of chronic feed-ing (3-4 wk) of the hydrophobic surfact...
acid-1-14C, and palmitic acid-9,10-3H) was infused intraduodenally at a steady rate for 8 hr in fast...
The mechanism underlying subcutaneous absorption of macro-molecules and factors that can influence t...
ABSTRACT. Background: Medium-chain triglycerides are used for the treatment of malabsorptive states....
A technique for collection of intestinal lymph in non-restrained rats has been developed. The lymph ...
Oil and emulsion vehicles have been shown to alter the oral absorption of many drugs. This may be du...
The triglyceride (TG) mimetic prodrug (1,3-dipalmitoyl-2-mycophenoloyl glycerol, 2-MPA-TG) biochemic...
[EN]: Some compounds, other than fatty anilides, which had been isolated from oil samples involved i...
Many lipophilic compounds are absorbed to some degree via the lymphatics, however, the mechanisms an...
The retinoids are highly lipophilic molecules and are known to be transported in the intestinal lymp...
[3H]Arachidonic (20:4) and [14C]linoleic acid (18:2) were fed to thoracic duct-cannulated rats in te...
The purpose of this study was to measure the pharmacokinetics and tissue accumulation of N-acetylami...
Drugs are commonly administered via the intraperitoneal (IP) route to treat localized infections and...
The lymphatic system plays a number of roles in key physiological and pathological events, including...
The plasma-lymphatic distribution of ribonuclease (RNase), superoxide dismutase (SODase), and catala...
Liver Physiol. 2): GMLG353, 1980. The effect of chronic feed-ing (3-4 wk) of the hydrophobic surfact...
acid-1-14C, and palmitic acid-9,10-3H) was infused intraduodenally at a steady rate for 8 hr in fast...
The mechanism underlying subcutaneous absorption of macro-molecules and factors that can influence t...
ABSTRACT. Background: Medium-chain triglycerides are used for the treatment of malabsorptive states....
A technique for collection of intestinal lymph in non-restrained rats has been developed. The lymph ...
Oil and emulsion vehicles have been shown to alter the oral absorption of many drugs. This may be du...
The triglyceride (TG) mimetic prodrug (1,3-dipalmitoyl-2-mycophenoloyl glycerol, 2-MPA-TG) biochemic...