Host membrane remodeling is indispensable for viruses, bacteria, and parasites, to subvert the membrane barrier and obtain entry into cells. The malaria parasite Plasmodium spp. induces biophysical and molecular changes to the erythrocyte membrane through the ordered secretion of its apical organelles. To understand this process and address the debate regarding how the parasitophorous vacuole membrane (PVM) is formed, we developed an approach using lattice light-sheet microscopy, which enables the parasite interaction with the host cell membrane to be tracked and characterized during invasion. Our results show that the PVM is predominantly formed from the erythrocyte membrane, which undergoes biophysical changes as it is remodeled across al...
Little is known about the molecular mechanisms underlying the release of merozoites from malaria inf...
Little is known about the molecular mechanisms underlying the release of merozoites from malaria inf...
SummaryThree opposing pathways are proposed for the release of malaria parasites [1] from infected e...
Here, Geoghegan, Evelyn et al. provide a lattice light-sheet microscopy based 4D imaging pipeline to...
When a malaria parasite invades a host erythrocyte it pushes itself in and invaginates a portion of ...
When a malaria parasite invades a host erythrocyte it pushes itself in and invaginates a portion of ...
During asexual replication within the Anopheles mosquito and their vertebrate host, Plasmodium paras...
© 2019 Dr. Oliver Creighton JasperAfter invading a human red blood cell (RBC), Plasmodium falciparum...
Erythrocyte invasion by the malaria parasite P. falciparum is a complex molecular process encompassi...
In the asexual blood stages of malarial infection, merozoites invade erythrocytes and replicate with...
The protozoan parasite Plasmodium is transmitted by female Anopheles mosquitoes and undergoes obliga...
SUMMARYThe asexual intraerythrocytic development of; Plasmodium falciparum; , causing the most sever...
The pathology of malaria is caused by infection of red blood cells with unicellular Plasmodium paras...
Plasmodium falciparum is the protozoan parasite that causes the most virulent of human malarias. The...
Little is known about the molecular mechanisms underlying the release of merozoites from malaria inf...
Little is known about the molecular mechanisms underlying the release of merozoites from malaria inf...
Little is known about the molecular mechanisms underlying the release of merozoites from malaria inf...
SummaryThree opposing pathways are proposed for the release of malaria parasites [1] from infected e...
Here, Geoghegan, Evelyn et al. provide a lattice light-sheet microscopy based 4D imaging pipeline to...
When a malaria parasite invades a host erythrocyte it pushes itself in and invaginates a portion of ...
When a malaria parasite invades a host erythrocyte it pushes itself in and invaginates a portion of ...
During asexual replication within the Anopheles mosquito and their vertebrate host, Plasmodium paras...
© 2019 Dr. Oliver Creighton JasperAfter invading a human red blood cell (RBC), Plasmodium falciparum...
Erythrocyte invasion by the malaria parasite P. falciparum is a complex molecular process encompassi...
In the asexual blood stages of malarial infection, merozoites invade erythrocytes and replicate with...
The protozoan parasite Plasmodium is transmitted by female Anopheles mosquitoes and undergoes obliga...
SUMMARYThe asexual intraerythrocytic development of; Plasmodium falciparum; , causing the most sever...
The pathology of malaria is caused by infection of red blood cells with unicellular Plasmodium paras...
Plasmodium falciparum is the protozoan parasite that causes the most virulent of human malarias. The...
Little is known about the molecular mechanisms underlying the release of merozoites from malaria inf...
Little is known about the molecular mechanisms underlying the release of merozoites from malaria inf...
Little is known about the molecular mechanisms underlying the release of merozoites from malaria inf...
SummaryThree opposing pathways are proposed for the release of malaria parasites [1] from infected e...