The aim of this article is to re-examine the duality of subject (of knowledge) vs. object (knowable) and to argue for its renewal and, ultimately, its overcoming in the light of Greimasian and postgreimasian semiotics, as well as of Étienne Souriau's plurimodal ontology. To this end, a set of key concepts – the meaning of being and the being of meaning, subjectivity and objectivity, presence, event, point of view, imperfection, letting be and letting do, making be and making do, the one and the multiple, singularity and arrangement – are analysed from the point of view of semiotics and of Souriau's theory of “instauration”. Next, the article proposes to study the role played, in semiotics, by the general modes of synaptic, modality and alte...