Background Over two million children experience homelessness annually in the United States, often disrupting their healthcare. The purpose of this study, spearheaded by the National Network to End Family Homelessness (NNEFH), was to understand the role of primary care providers who serve children and families experiencing homelessness. Specifically, we sought to describe best practices for screening for housing-unstable families and providing optimal care for these patients once identified. MethodsWe conducted a qualitative study employing semi-structured, in-depth interviews with clinicians and administrators working in healthcare organizations serving children and families. Recruitment occurred by invitation from NNEFH Health Committee me...