Graphical representation of the sequence conservation of amino acids (sequence logo) for DRB exon 2.

Compares site variability between Cebus (A), Sapajus (B), Platyrrhini (C), Cercopithecoidea (D) and Hominoidea (E). Single letter codes are shown for amino acids and colors indicate their major biochemical properties: Red–acidic; Blue–basic; Green–polar; Black–hydrophobic. Generated using WebLogo [84]. Gray shading indicates predicted PBR (peptide binding region) sites based on human PBR in [39]. Letters in the top row indicate the most common amino acid at that site in human HLA alleles [39].