Representative images of single motoneuron cell bodies which co-express indicated RNAi via the D42-Gal4 driver, together with the full-length tagged matrix protein Idh3b-HA (UAS-Idh3b-HA). Idh3b is detected based on antibody staining for the HA tag (cyan). White arrowheads indicate PolyUb+ (red) mitophagy intermediates that lack Idh3b-HA. Scale bar = 2μm. (TIF)</p
<p>(A) hFAM173B-GFP (green) colocalized with the mitochondrial dye MitoTrackerRedCMXROS but not with...
BACKGROUND: Respiratory chain (RC) deficiencies are found in primary mtDNA diseases. Focal RC defect...
<p>A) Brain sections were stained with anti-synaptophysin (green), anti-ATP synthase β subunit (red)...
Representative images of single motoneuron cell bodies which express Vps13D RNAi via the D42-Gal4 dr...
Representative images of motoneurons in the larval VNC which co-express UAS-mitoGFP (cyan) with UAS-...
A) Representative images of individual larval motoneurons which co-express mitochondrial marker mito...
A) Representative images of individual dorsal midline motoneuron cell bodies co-expressing the indic...
A) Representative images of motoneurons in the larval VNC which co-express the mitochondrial marker ...
A) Two-hit model for mitophagy intermediates lacking matrix (cyan), but containing IMM (yellow) that...
A,C,E) Representative images of dorsal midline motoneurons in larval VNCs from a wildtype background...
A) Representative images of individual dorsal midline motoneuron cell bodies co-expressing the indic...
A) Representative images of individual mitophagy intermediates engaged with a range of phagophore si...
Representative images of dorsal midline motoneurons in early second instar larval VNCs from a Vps13D...
A) Two examples of larval neurons expressing Vps13D-RNAi which contain mitochondria engaged with a p...
A) Representative images of live larval motoneurons expressing UAS-mCherry-GFP-Atg8A, expressed via ...
<p>(A) hFAM173B-GFP (green) colocalized with the mitochondrial dye MitoTrackerRedCMXROS but not with...
BACKGROUND: Respiratory chain (RC) deficiencies are found in primary mtDNA diseases. Focal RC defect...
<p>A) Brain sections were stained with anti-synaptophysin (green), anti-ATP synthase β subunit (red)...
Representative images of single motoneuron cell bodies which express Vps13D RNAi via the D42-Gal4 dr...
Representative images of motoneurons in the larval VNC which co-express UAS-mitoGFP (cyan) with UAS-...
A) Representative images of individual larval motoneurons which co-express mitochondrial marker mito...
A) Representative images of individual dorsal midline motoneuron cell bodies co-expressing the indic...
A) Representative images of motoneurons in the larval VNC which co-express the mitochondrial marker ...
A) Two-hit model for mitophagy intermediates lacking matrix (cyan), but containing IMM (yellow) that...
A,C,E) Representative images of dorsal midline motoneurons in larval VNCs from a wildtype background...
A) Representative images of individual dorsal midline motoneuron cell bodies co-expressing the indic...
A) Representative images of individual mitophagy intermediates engaged with a range of phagophore si...
Representative images of dorsal midline motoneurons in early second instar larval VNCs from a Vps13D...
A) Two examples of larval neurons expressing Vps13D-RNAi which contain mitochondria engaged with a p...
A) Representative images of live larval motoneurons expressing UAS-mCherry-GFP-Atg8A, expressed via ...
<p>(A) hFAM173B-GFP (green) colocalized with the mitochondrial dye MitoTrackerRedCMXROS but not with...
BACKGROUND: Respiratory chain (RC) deficiencies are found in primary mtDNA diseases. Focal RC defect...
<p>A) Brain sections were stained with anti-synaptophysin (green), anti-ATP synthase β subunit (red)...