Solubility Correlations. Part 1: Simultaneous Fitting of Both Solute and Solvent Properties

A method is described for estimating solubility by fitting both solute and solvent properties in a single equation. The method is illustrated by examining the solubilities of five rare gases (He, Ne, Ar, Kr, Xe) and five ‘permanent’ gases (O2, N2, CH4, CF4, SF6) in either n-alkane (C5H12to C16H34) or alkan-1-ol (CH3OH to C11H23OH) solvents. Generally, the correlation (R2) values of the fits achieved were significantly better than 0.9. It is suggested that similar methods can be used for estimating other physico-chemical properties such as excess molar volumes and enthalpies of solution