Theoretical models predict that core-collapse supernovae (CCSNe) can be efficient dust producers (0.1–1.0 M⊙), potentially accounting for most of the dust production in the early Universe. Observational evidence for this dust production efficiency is however currently limited to only a few CCSN remnants (e.g. SN 1987A, Crab nebula). In this paper, we revisit the dust mass produced in Cassiopeia A (Cas A), a ∼330-yr old O-rich Galactic supernova remnant (SNR) embedded in a dense interstellar foreground and background. We present the first spatially resolved analysis of Cas A based on Spitzer and Herschel infrared and submillimetre data at a common resolution of ∼0.6 arcmin for this 5 arcmin diameter remnant following a careful removal of con...