Ceruloplasmin gene variants are associated with hyperferritinemia and increased liver iron in patients with {NAFLD}
- Elena Corradini
- Elena Buzzetti
- Paola Dongiovanni
- Stefania Scarlini
- Angela Caleffi
- Serena Pelusi
- Isabella Bernardis
- Paolo Ventura
- Raffaela Rametta
- Elena Tenedini
- Enrico Tagliafico
- Anna Ludovica Fracanzani
- Silvia Fargion
- Antonello Pietrangelo
- Luca Vittorio Valenti
DOIAbstract
Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disorder resulting from genetic and environmental factors. Hyperferritinemia has been associated with increased hepatic iron stores and worse outcomes in patients with NAFLD. The aim of this study was to evaluate the prevalence of variants of iron-related genes and their association with hyperferritinemia, hepatic iron stores and liver disease severity in patients with NAFLD
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