Mainly motivated by the problem of modelling biological processes underlying the basic functions of a cell -that typically involve complex interactions between genes- we present a new algorithm, called PC-LPGM, for learning the structure of undirected graphical models over discrete variables. We prove theoretical consistency of PC-LPGM in the limit of infinite observations and discuss its robustness to model misspecification. To evaluate the performance of PC-LPGM in recovering the true structure of the graphs in situations where relatively moderate sample sizes are available, extensive simulation studies are conducted, that also allow to compare our proposal with its main competitors. A biological validation of the algorithm is presented t...
<p>Gaussian graphical models represent the underlying graph structure of conditional dependence betw...
Statistical models of the amino acid composition of the proteins within a fold family are widely use...
This thesis shows a novel contribution to computational biology alongside with developed ma-chine le...
Mainly motivated by the problem of modelling biological processes underlying the basic functions of ...
Biological processes underlying the basic functions of a cell involve complex interactions between g...
This electronic version was submitted by the student author. The certified thesis is available in th...
AbstractWhen it comes to learning graphical models from data, approaches based on conditional indepe...
<p>Undirected graphical models are important in a number of modern applications that involve explori...
Decoding complex relationships among large numbers of variables with relatively few observations is ...
Gene expression datasets consist of thousand of genes with relatively small samplesizes (i.e. are la...
This dissertation explores the undirected graphical model framework. We explore applications of hig...
The main topic of the doctoral thesis revolves around learning the structure of a graphical model fr...
Undirected probabilistic graphical models represent the conditional dependencies, or Markov properti...
Background: Various l(1)-penalised estimation methods such as graphical lasso and CLIME are widely u...
Abstract Background Various ℓ ...
<p>Gaussian graphical models represent the underlying graph structure of conditional dependence betw...
Statistical models of the amino acid composition of the proteins within a fold family are widely use...
This thesis shows a novel contribution to computational biology alongside with developed ma-chine le...
Mainly motivated by the problem of modelling biological processes underlying the basic functions of ...
Biological processes underlying the basic functions of a cell involve complex interactions between g...
This electronic version was submitted by the student author. The certified thesis is available in th...
AbstractWhen it comes to learning graphical models from data, approaches based on conditional indepe...
<p>Undirected graphical models are important in a number of modern applications that involve explori...
Decoding complex relationships among large numbers of variables with relatively few observations is ...
Gene expression datasets consist of thousand of genes with relatively small samplesizes (i.e. are la...
This dissertation explores the undirected graphical model framework. We explore applications of hig...
The main topic of the doctoral thesis revolves around learning the structure of a graphical model fr...
Undirected probabilistic graphical models represent the conditional dependencies, or Markov properti...
Background: Various l(1)-penalised estimation methods such as graphical lasso and CLIME are widely u...
Abstract Background Various ℓ ...
<p>Gaussian graphical models represent the underlying graph structure of conditional dependence betw...
Statistical models of the amino acid composition of the proteins within a fold family are widely use...
This thesis shows a novel contribution to computational biology alongside with developed ma-chine le...