Schizophrenia, a severe psychiatric disorder with symptoms that emerge predominately in young adulthood, is thought to result from disruptions in the normal course of neurodevelopment. One of the most reproducible findings with respect to schizophrenia is altered function of the mesocorticolimbic dopamine (DA) system. As such, perturbed function of proteins that organize the development of this system could be a contributing factor underlying the etiology of this disorder. Work from the laboratory of Dr. Flores has shown that the netrin-1 guidance cue receptor, deleted in colorectal cancer (DCC), is highly expressed in mesocorticolimbic DA neurons from embryonic life through adulthood and is critically involved in the adolescent organizatio...
Repeated exposure to psychostimulants activates mesocorticolimbic dopamine (DA), resulting in an inc...
Les récepteurs à dépendance présentent la particularité d’induire deux voies de signalisation différ...
Repeated exposure to amphetamine (AMPH) induces sensitization to its behavioral-activating effects. ...
The netrin-1 receptor DCC (deleted in colorectal cancer) has been well established as a protein invo...
DCC (deleted in colorectal cancer), a receptor for the axon guidance cue netrin-1, is highly express...
The netrin-1 receptor, DCC, determines a) the extent of dopamine innervation to the medial prefronta...
The fine arrangement of neuronal connectivity during development involves the coordinated action of ...
The secreted protein netrin-1 has diverse functions among which guidance and survival of neurons whe...
The netrin-1 guidance cue and its receptors, DCC and UNC5H, contribute to the organization and funct...
Adolescence is a dynamic period of life, marked by dramatic physical, hormonal, and behavioral chang...
The role of axon guidance cues during development has been extensively investigated. However, the ex...
Neural circuits are the basis of the human experience. The long journey from birth to becoming a fu...
Axon guidance cues such as netrin-1 are known to be important for the development of neural circuits...
Sherpa Romeo green journal, open accessAdolescence is a period of heightened susceptibility to psych...
While it is well known that netrin-1 and its receptor Deleted in Colorectal Cancer (DCC) are essenti...
Repeated exposure to psychostimulants activates mesocorticolimbic dopamine (DA), resulting in an inc...
Les récepteurs à dépendance présentent la particularité d’induire deux voies de signalisation différ...
Repeated exposure to amphetamine (AMPH) induces sensitization to its behavioral-activating effects. ...
The netrin-1 receptor DCC (deleted in colorectal cancer) has been well established as a protein invo...
DCC (deleted in colorectal cancer), a receptor for the axon guidance cue netrin-1, is highly express...
The netrin-1 receptor, DCC, determines a) the extent of dopamine innervation to the medial prefronta...
The fine arrangement of neuronal connectivity during development involves the coordinated action of ...
The secreted protein netrin-1 has diverse functions among which guidance and survival of neurons whe...
The netrin-1 guidance cue and its receptors, DCC and UNC5H, contribute to the organization and funct...
Adolescence is a dynamic period of life, marked by dramatic physical, hormonal, and behavioral chang...
The role of axon guidance cues during development has been extensively investigated. However, the ex...
Neural circuits are the basis of the human experience. The long journey from birth to becoming a fu...
Axon guidance cues such as netrin-1 are known to be important for the development of neural circuits...
Sherpa Romeo green journal, open accessAdolescence is a period of heightened susceptibility to psych...
While it is well known that netrin-1 and its receptor Deleted in Colorectal Cancer (DCC) are essenti...
Repeated exposure to psychostimulants activates mesocorticolimbic dopamine (DA), resulting in an inc...
Les récepteurs à dépendance présentent la particularité d’induire deux voies de signalisation différ...
Repeated exposure to amphetamine (AMPH) induces sensitization to its behavioral-activating effects. ...