To study the influence on liver cancer by bear bile powder and its common content ursodeoxycholic acid

世界范围内，原发性肝癌（以下简称肝癌）在所有恶性肿瘤中，发病率第5位，死亡率第3位，其中半数以上发生于中国。肝癌通常发生于慢性肝病、肝硬化的基础上，大部分患者发现时已是中晚期肝癌，虽然治疗方法众多，但总体疗效不佳，亟需寻找更好的防治策略。一方面应高度重视乙肝疫苗接种等干预措施从根源上阻断肝癌，另一方面应积极开拓更好的治疗方法和源头创新药物。近年来中医药防治肝癌受到重视，因其整体观更强并能兼顾治疗基础性慢性肝病，提高患者的整体机能、改善生存质量、延长带瘤生存时间。 熊胆是传统名贵中药，因为保肝、利胆疗效显著，临床广泛应用于治疗各种慢性肝病，其主要成分熊去氧胆酸（UDCA）是FDA批准应用于治疗...Primary liver cancer (hereinafter referred to liver cancer) is a malignant tumor. The incidence was the fifth and the mortality was the third worldwide, and more than half of them occured in China. Liver cancer usually developed from chronic liver disease and cirrhosis. Most patients are diagnosed of hepatocellular carcinoma in late stage, though there are many kinds of treatments, the prognosis i...学位：理学博士院系专业：医学院_生理学学号：2452009015419