The research proposes an author\u27s view of the variety of methods and their practical application in work with children with combined developmental disabilities. In the course of professional activity in Rezekne Elementary Boarding School - Development Center (REBS-DC) during the period from 2012 to 2018, the most effective methods for integrating children with combined disabilities into the learning process and promoting their development and future integration into society were selected, analyzed and used in practice.Research objective: to provide insights into the variety of methods and their effectiveness in work with a child with combined disabilities.Research methods: reflection on experience, analysis of scientific literature