Characterization of PHF11, a candidate tumor suppressor gene, in esophageal squamous cell carcinoma

Poster Session 7 - Nuclear Oncogenes and Tumor Suppressor Genes: abstract no. 2181BACKGROUND AND AIMS: Esophageal squamous cell carcinoma (ESCC) has a high incidence in China, with five-year survival rates in Hong Kong of only 10.7%. Loss of chromosome 13q regions is a frequent event in ESCC. A candidate tumor suppressor gene (TSG), PHF11, located at 13q14.2 was identified from our previous chromosome transfer study and shows 100% down-regulation in 18 cancer cell lines, including 16 ESCC cell lines, compar...link_to_OA_fulltex