The current definition of schizophrenia indicates that it is a term reserved for idiopathic cases of chronic psychosis. It may prove to be a cluster of different illnesses, with similar and overlapping symptoms. Schizophrenia is of multifactorial origin. Both genetic and environmental factors have been associated with an increased risk for schizophrenia. This paper is a review of some aspects of the history, symptoms, treatments and experimental models of schizophrenia.La définition actuelle de la schizophrénie reste celle d'une psychose chronique idiopathique. Ce status quo pourrait être dû à la multiplicité des affections rassemblées sous un même diagnostic. Il pourrait s'agir d'une maladie multifactorielle dont la survenue dépendrait d'u...