International audienceUsing both an atmospheric global circulation model and a regional oceanic model, we assess the impact of the Andes uplift on the Humboldt Current system (HCS). With three topographic scenarios for the Andes, we show that the uplift played a crucial role in shaping the lower troposphere dynamics over the Pacific Ocean and in turn affected the physical characteristics of the system. Our results show that the uplift has triggered a marked southward shift of the HCS, changing the latitudinal position of coastal upwelling areas as well as the strength of the South Pacific gyre. Our oceanic modeling experiments show that the latitudinal pattern of sea surface temperatures is dramatically modified with reduced Andes, with ano...