Hobuste endometriidi diagnoosimine ja ravi - Eesti praktika

Graduation Thesis Curricula of Veterinary MedicineEquine endometritis, inflammation of uterine inner layer, is described as one of the major causes of infertility in horses. The aim was to observe used diagnosing and treatment protocols in one Estonian practice, follow the treatment outcome and study the complex of this disease as whole. Study was based on one Estonian equine practitioner’s breeding datasheet gathered in season 2017. Data was collected from EquiBreedVet reproduction management database and processed with Microsoft Excel. Also, laboratory results were included in the study. Observation of clinical practice was performed in spring 2018. In breeding season 2017 in total 76 mares were intended to be bred in this veterinarian practice. Infectious endometritis was found from nine mares, with the frequency of 11,8% in studied population. The main microbes isolated were genital commensals E.coli and Streptococcus equi ssp. zooepidemicus. Two mares developed a fungal infection which was caused by Candida ssp. Pregnancy rates in infected mares was considerably lower compared to healthy mares (44,4 vs. 84,4%). Infected mares were also older (8,9 vs. 11,7 years). The pathological findings and frequency were similar as presented in the literature. Methods in researched practice were evidence based. Used diagnostic and treatment protocols were similar as the methods in literature. Antimicrobial treatment was based on pathogens sensitivity. To improve diagnostics biopsy from endometrium could be added in diagnostic protocol. Also, uterine lavage as treatment option might be demonstrated more often and additionally used in combination together with antibiotics.Hobuste endometriit, ehk emaka sisekesta põletik, on kirjeldatud kui ühte peamist ahtruse põhjust hobustel. Eesmärk oli selgitada hobuste infektsioosse endometriidi ravi ja diagnoosimise protokolle ühes Eesti praksises, selgitada välja ravitulemused ja uurida haigust üldiselt. Uuring põhines ühe Eesti hobusearsti andmetele mis oli kogutud ühe sigimise hooaja jooksul aastal 2017. Andmed koguti EquiBreedVet haldamisüsteemiga ning sorteeriti Microsoft Excel’i abil. Uuring sisaldas ka laboratoorseid tulemusi. Tutvumine praksise tööga toimus kevadel 2018. 2017 aastal püüti tiinestada 76 mära. Infektsioosne endometriit tuvastati üheksal märal ehk 11,8% märadest. Peamised infektsiooni tekitaja olid E.coli ja Streptococcus equi ssp. zooepidemicus. Kahel märal tekkisid seeneinfektsioonid, mille põhjustaks olid Candida ssp. Tiinestumine haigestunud märadel oli tunduvalt halvem kui tervetel märadel (44,4% vs 84,4%). Avasti ka et endometriidiga märad olid vanemad (8,9 vs 11,7a). Eesti praksise patoloogilised leiud ning haigete märade osakaal vastas kirjanduses kirjeldatule. Praksise töötamisviisid olid asjakohased. Diagnoosimise- ja raviskeemid vastasid kirjandusele, antimikrobiaalne ravi põhines avastatud patogeenide tundlikkusel. Emakapõletike diagnoosimist saaks parandada emakasisekesta-biopsiate võtmist kasutades ning ravis emakaloputuste osakaalu võiks suurendada, ka siis kui kasutusel on antimikrobiaalne ravi