Tumor necrosis factor a (TNFα) has been shown to trigger many signaling pathways. Following oligomerization by TNFα, the receptors TNF-RI and TNF-RI1 associate with adapter molecules via specific protein-protein interactions. The subsequent recruitment of downstream molecules to the receptor complex enables propagation of the TNFα signal. l k o cellular responses to TNFα have been well documented, the induction of cell death and the activation of gene transcription for cell survival. TNFα-induced apoptosis involves the activation of caspase cascades, which culminate in the cleavage of specific cellular substrates to effect cell death. TNFα has also been implicated in various caspase-independent cell death processes. Two transcription factor...
Like other members of the tumor necrosis factor (TNF) receptor family, p55 TNF receptor 1 (TNF-R1) l...
Present adress of Olivier Micheau: INSERM U517, Faculties of Medicine and Pharmacy, 7 Bd Jeanne d'Ar...
Present adress of Olivier Micheau: INSERM U517, Faculties of Medicine and Pharmacy, 7 Bd Jeanne d'Ar...
Tumor necrosis factor a (TNFα) has been shown to trigger many signaling pathways. Following oligomer...
Early events in the signalling of tumor necrosis factor-receptor 1 (TNF-R1), which is the main TNF r...
Tumor necrosis factor (TNF) is an important cytokine with multiple biological effects, including cel...
<p>TNF-mediated death and survival pathways are activated following interaction with the TNFRs. The ...
In this review, we discuss the signal-transduction pathways of three major cellular responses induce...
In this review, we discuss the signal-transduction pathways of three major cellular responses induce...
<p>TNFα acts via its death domain containing receptor TNFR1 to activate caspase 8/10 and promote apo...
In this review, we discuss the signal-transduction pathways of three major cellular responses induce...
In this review, we discuss the signal-transduction pathways of three major cellular responses induce...
Firstly, we demonstrated that caspase-dependent cell death was enhanced by the over-expression of th...
AbstractApoptosis induced by TNF-receptor I (TNFR1) is thought to proceed via recruitment of the ada...
Present adress of Olivier Micheau: INSERM U517, Faculties of Medicine and Pharmacy, 7 Bd Jeanne d'Ar...
Like other members of the tumor necrosis factor (TNF) receptor family, p55 TNF receptor 1 (TNF-R1) l...
Present adress of Olivier Micheau: INSERM U517, Faculties of Medicine and Pharmacy, 7 Bd Jeanne d'Ar...
Present adress of Olivier Micheau: INSERM U517, Faculties of Medicine and Pharmacy, 7 Bd Jeanne d'Ar...
Tumor necrosis factor a (TNFα) has been shown to trigger many signaling pathways. Following oligomer...
Early events in the signalling of tumor necrosis factor-receptor 1 (TNF-R1), which is the main TNF r...
Tumor necrosis factor (TNF) is an important cytokine with multiple biological effects, including cel...
<p>TNF-mediated death and survival pathways are activated following interaction with the TNFRs. The ...
In this review, we discuss the signal-transduction pathways of three major cellular responses induce...
In this review, we discuss the signal-transduction pathways of three major cellular responses induce...
<p>TNFα acts via its death domain containing receptor TNFR1 to activate caspase 8/10 and promote apo...
In this review, we discuss the signal-transduction pathways of three major cellular responses induce...
In this review, we discuss the signal-transduction pathways of three major cellular responses induce...
Firstly, we demonstrated that caspase-dependent cell death was enhanced by the over-expression of th...
AbstractApoptosis induced by TNF-receptor I (TNFR1) is thought to proceed via recruitment of the ada...
Present adress of Olivier Micheau: INSERM U517, Faculties of Medicine and Pharmacy, 7 Bd Jeanne d'Ar...
Like other members of the tumor necrosis factor (TNF) receptor family, p55 TNF receptor 1 (TNF-R1) l...
Present adress of Olivier Micheau: INSERM U517, Faculties of Medicine and Pharmacy, 7 Bd Jeanne d'Ar...
Present adress of Olivier Micheau: INSERM U517, Faculties of Medicine and Pharmacy, 7 Bd Jeanne d'Ar...