450K Epigenome-Wide Scan Identifies Differential DNA Methylation in Newborns Related to Maternal Smoking during Pregnancy
- Joubert, Bonnie R.
- Håberg, Siri E.
- Nilsen, Roy M.
- Wang, Xuting
- Vollset, Stein E.
- Murphy, Susan K.
- Huang, Zhiqing
- Hoyo, Cathrine
- Midttun, Øivind
- Cupul-Uicab, Lea A.
- Ueland, Per M.
- Wu, Michael C.
- Nystad, Wenche
- Bell, Douglas A.
- Peddada, Shyamal D.
- London, Stephanie J.
Publication date
January 2012
DOIAbstract
Background: Epigenetic modifications, such as DNA methylation, due to in utero exposures may play a critical role in early programming for childhood and adult illness. Maternal smoking is a major risk factor for multiple adverse health outcomes in children, but the underlying mechanisms are unclear
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