Pharmacokinetic Modelling of Efavirenz, Atazanavir, Lamivudine and Tenofovir in the Female Genital Tract of HIV-Infected Pre-Menopausal Women
- Dumond, Julie B.
- Nicol, Melanie R.
- Kendrick, Racheal N.
- Garonzik, Samira M.
- Patterson, Kristine B.
- Cohen, Myron S.
- Forrest, Alan
- Kashuba, Angela D.M.
Publication date
January 2012
DOIAbstract
A previously published study of antiretroviral pharmacokinetics in the female genital tract of HIV-infected women demonstrated differing degrees of female genital tract penetration among antiretrovirals. These blood plasma (BP) and cervicovaginal fluid (CVF) data were co-modelled for four antiretrovirals with varying CVF exposures
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