Multi-Ethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRI
- Verhaaren, Benjamin F.J.
- Debette, Stéphanie
- Bis, Joshua C.
- Smith, Jennifer A.
- Ikram, M. Kamran
- Adams, Hieab H.
- Beecham, Ashley H.
- Rajan, Kumar B.
- Lopez, Lorna M.
- Barral, Sandra
- Van Buchem, Mark A.
- Van Der Grond, Jeroen
- Smith, Albert V.
- Hegenscheid, Katrin
- Aggarwal, Neelum T.
- De Andrade, Mariza
- Atkinson, Elizabeth J.
- Beekman, Marian
- Beiser, Alexa S.
- Blanton, Susan H.
- Boerwinkle, Eric
- Brickman, Adam M.
- Bryan, R. Nick
- Chauhan, Ganesh
- Chen, Christopher P.L.H.
- Chouraki, Vincent
- De Craen, Anton J.M.
- Crivello, Fabrice
- Deary, Ian J.
- Deelen, Joris
- De Jager, Philip L.
- Dufouil, Carole
- Elkind, Mitchell S.V.
- Evans, Denis A.
- Freudenberger, Paul
- Gottesman, Rebecca F.
- Gunason, Vilmundur
- Habes, Mohamad
- Heckbert, Susan R.
- Heiss, Gerardo
- Hilal, Saima
- Hofer, Edith
- Hofman, Albert
- Ibrahim-Verbaas, Carla A.
- Knopman, David S.
- Lewis, Cora E.
- Liao, Jiemin
- Liewald, David C.M.
- Luciano, Michelle
- Van Der Lugt, Aad
- Martinez, Oliver O.
- Mayeux, Richard
- Mazoyer, Bernard
- Nalls, Mike
- Nauck, Matthias
- Niessen, Wiro J.
- Oostra, Ben A.
- Psaty, Bruce M.
- Rice, Kenneth M.
- Rotter, Jerome I.
- Von Sarnowski, Bettina
- Schmidt, Helena
- Schreiner, Pamela J.
- Schuur, Maaike
- Sidney, Stephen S.
- Sigurdsson, Sigurdur
- Slagboom, P. Eline
- Stott, David J.M.
- Van Swieten, John C.
- Teumer, Alexander
- Töglhofer, Anna Maria
- Traylor, Matthew
- Trompet, Stella
- Turner, Stephen T.
- Tzourio, Christophe
- Uh, Hae Won
- Uitterlinden, André G.
- Vernooij, Meike W.
- Wang, Jing J.
- Wong, Tien Y.
- Wardlaw, Joanna M.
- Windham, B. Gwen
- Wittfeld, Katharina
- Wolf, Christiane
- Wright, Clinton B.
- Yang, Qiong
- Zhao, Wei
- Zijdenbos, Alex
- Jukema, J. Wouter
- Sacco, Ralph L.
- Kardia, Sharon L.R.
- Amouyel, Philippe
- Mosley, Thomas H.
- Longstreth, W. T.
- DeCarli, Charles C.
- Van Duijn, Cornelia M.
- Schmidt, Reinhold
- Launer, Lenore J.
- Grabe, Hans J.
- Seshadri, Sudha S.
- Ikram, M. Arfan
- Fornage, Myriam
Publication date
January 2015
DOIAbstract
The burden of cerebral white matter hyperintensities (WMH) is associated with an increased risk of stroke, dementia, and death. WMH are highly heritable, but their genetic underpinnings are incompletely characterized. To identify novel genetic variants influencing WMH burden, we conducted a meta-analysis of multi-ethnic genome-wide association studies
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