Add to ORKGTissue inhibitors of metalloproteinases (TIMPs) play a key regulatory role in the homeostasis of the extracellular matrix (ECM) by controlling the activity of matrix metalloproteinases (MMPs). Some TIMPs have a second function as well, unrelated to their antiMMP activity, which affects cell proliferation and survival. The role of these inhibitors in cancer has been the subject of extensive investigations that have examined their biological activity in tumor growth, invasion, metastasis and angiogenesis, as well as their potential use in the diagnosis and treatment of human cancer
Esophageal cancer (EC) is one of the most aggressive malignant tumors of the gastrointestinal tract....
In the past decades, a lot of effort has been put in identifying the role of matrix metalloproteinas...
In the past decades, a lot of effort has been put in identifying the role of matrix metalloproteinas...
Tissue inhibitors of metalloproteinases (TIMPs) play a key regulatory role in the homeostasis of the...
Tissue inhibitors of matrix metalloproteinases (TIMPs) are a family of natural inhibitors that contr...
Tissue inhibitors of matrix metalloproteinases (TIMPs) are a family of natural inhibitors that contr...
The extracellular matrix (ECM) is constantly remodelled in healthy tissues; this is essential in nor...
Abstract Tissue inhibitors of metalloproteinases (TIMPs) regulate diverse processes, including extra...
Matrix metalloproteinases (MMPs) are both structural and catalytic proteolytic enzymes. Many MMPs ha...
Over the last twenty years the tissue inhibitors of metalloproteinases (TIMPs) have been implicated ...
Since Gross and Lapiere firstly discovered matrix metalloproteinases (MMPs) as important collagenoly...
Since Gross and Lapiere firstly discovered matrix metalloproteinases (MMPs) as important collagenoly...
Since Gross and Lapiere firstly discovered matrix metalloproteinases (MMPs) as important collagenoly...
Extracellular proteolysis mediates tissue homeostasis. In cancer, altered proteolysis leads to unreg...
Toth M, Bernardo MM, Gervasi DC, et al. Tissue inhibitor of metalloproteinase (TIMP)-2 acts synergis...
Esophageal cancer (EC) is one of the most aggressive malignant tumors of the gastrointestinal tract....
In the past decades, a lot of effort has been put in identifying the role of matrix metalloproteinas...
In the past decades, a lot of effort has been put in identifying the role of matrix metalloproteinas...
Tissue inhibitors of metalloproteinases (TIMPs) play a key regulatory role in the homeostasis of the...
Tissue inhibitors of matrix metalloproteinases (TIMPs) are a family of natural inhibitors that contr...
Tissue inhibitors of matrix metalloproteinases (TIMPs) are a family of natural inhibitors that contr...
The extracellular matrix (ECM) is constantly remodelled in healthy tissues; this is essential in nor...
Abstract Tissue inhibitors of metalloproteinases (TIMPs) regulate diverse processes, including extra...
Matrix metalloproteinases (MMPs) are both structural and catalytic proteolytic enzymes. Many MMPs ha...
Over the last twenty years the tissue inhibitors of metalloproteinases (TIMPs) have been implicated ...
Since Gross and Lapiere firstly discovered matrix metalloproteinases (MMPs) as important collagenoly...
Since Gross and Lapiere firstly discovered matrix metalloproteinases (MMPs) as important collagenoly...
Since Gross and Lapiere firstly discovered matrix metalloproteinases (MMPs) as important collagenoly...
Extracellular proteolysis mediates tissue homeostasis. In cancer, altered proteolysis leads to unreg...
Toth M, Bernardo MM, Gervasi DC, et al. Tissue inhibitor of metalloproteinase (TIMP)-2 acts synergis...
Esophageal cancer (EC) is one of the most aggressive malignant tumors of the gastrointestinal tract....
In the past decades, a lot of effort has been put in identifying the role of matrix metalloproteinas...
In the past decades, a lot of effort has been put in identifying the role of matrix metalloproteinas...