Non-Acidic Mediated Friedel-Craft Reaction of Thiophene Using EtAlCl2

WOS: 000325204200122Since alkyl Lewis acids are Bronsted bases, they give a non-acidic reaction media. In this context, acylation of thiophene is investigated in the presence of EtAlCl2 and non-acidic media. Besides 8 examples of thiophene, one example for pyrrole is synthesized in moderate to high yields (up to 99 %)